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Progressive glutathione depletion across trimesters : First trimester: 36% LOWER than non-pregnant Second trimester: 55% LOWER Third trimester: 87% LOWER This generates more NAPQI at precisely the time when glutathione reserves are least able to neutralize itcreating maximum vulnerability

Because no data points were missing from the SFNSL questionnaire, these data were analyzed by using repeated-measures analysis of variance (ANOVA)